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TIN2 Polyclonal Antibody

商品貨號(hào)： PLA018420

適應(yīng) 性： 人,大鼠,小鼠,

￥600元

規(guī)格：

40μL 100μL 200μL

在線咨詢(xún)

MSDS

說(shuō)明書(shū)

商品描述

基因名稱(chēng)： TINF2
蛋白名稱(chēng)： TERF1-interacting nuclear factor 2
Human_gene_id： 26277
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26277
Human_swiss_prot_no： Q9BSI4
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9BSI4/entry
Mouse_swiss_prot_no： Q9QXG9
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9QXG9
特異性： TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
實(shí)測(cè)條帶： 53kD
功能： alternative products:Experimental confirmation may be lacking for some isoforms,disease:Defects in TINF2 are a cause of dyskeratosis congenita autosomal dominant (ADDKC) [MIM:127550]; also known as dyskeratosis congenita Scoggins type. ADDKC is a rare, progressive bone marrow failure syndrome characterized by the triad of reticulated skin hyperpigmentation, nail dystrophy, and mucosal leukoplakia. Early mortality is often associated with bone marrow failure, infections, fatal pulmonary complications, or malignancy.,disease:Defects in TINF2 are a cause of retinopathy exudative with bone marrow failure (ERBMF) [MIM:268130]; also known as Revesz syndrome. ERBMF is characterized by bilateral exudative retinopathy, bone marrow hypoplasia, nail dystrophy, fine hair, cerebellar hypoplasia, and growth retardation.,function:Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly.,subcellular location:Associated with telomeres.,subunit:Monomer. Found in a complex with POT1; TERF1 and TNKS1. Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Binds to TERF1 and ACD.,tissue specificity:Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Chromosome, telomere . Associated with telomeres.; [Isoform 1]: Nucleus matrix .
組織表達(dá)： Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
科研貨號(hào)： PLA018420

TIN2 Polyclonal Antibody

Catalog No PLA018420

Product information

基因名稱(chēng)： TINF2
蛋白名稱(chēng)： TERF1-interacting nuclear factor 2
Human_gene_id： 26277
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26277
Human_swiss_prot_no： Q9BSI4
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9BSI4/entry
Mouse_swiss_prot_no： Q9QXG9
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9QXG9
特異性： TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來(lái)源： Polyclonal, Rabbit,IgG
稀釋?zhuān)? WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說(shuō)明書(shū)： 1
Msds： MSDS_Antibody.pdf
其他名稱(chēng)： TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
實(shí)測(cè)條帶： 53kD
功能： alternative products:Experimental confirmation may be lacking for some isoforms,disease:Defects in TINF2 are a cause of dyskeratosis congenita autosomal dominant (ADDKC) [MIM:127550]; also known as dyskeratosis congenita Scoggins type. ADDKC is a rare, progressive bone marrow failure syndrome characterized by the triad of reticulated skin hyperpigmentation, nail dystrophy, and mucosal leukoplakia. Early mortality is often associated with bone marrow failure, infections, fatal pulmonary complications, or malignancy.,disease:Defects in TINF2 are a cause of retinopathy exudative with bone marrow failure (ERBMF) [MIM:268130]; also known as Revesz syndrome. ERBMF is characterized by bilateral exudative retinopathy, bone marrow hypoplasia, nail dystrophy, fine hair, cerebellar hypoplasia, and growth retardation.,function:Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly.,subcellular location:Associated with telomeres.,subunit:Monomer. Found in a complex with POT1; TERF1 and TNKS1. Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Binds to TERF1 and ACD.,tissue specificity:Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Nucleus . Chromosome, telomere . Associated with telomeres.; [Isoform 1]: Nucleus matrix .
組織表達(dá)： Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
科研貨號(hào)： PLA018420

Hunan UPT Biotechnology Co.,Ltd

Website：www.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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