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Elmo1 Polyclonal Antibody

商品貨號： PLA018764

適應(yīng) 性： 人,小鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： ELMO1
蛋白名稱： Engulfment and cell motility protein 1
Human_gene_id： 9844
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9844
Human_swiss_prot_no： Q92556
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q92556/entry
Mouse_gene_id： 140580
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140580
Mouse_swiss_prot_no： Q8BPU7
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8BPU7
特異性： Elmo1 Polyclonal Antibody detects endogenous levels of Elmo1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： ELMO1; KIAA0281; Engulfment and cell motility protein 1; Protein ced-12 homolog
實測條帶： 83kD
信號通路： Chemokine;
功能： function:Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.,PTM:Phosphorylated by HCK.,similarity:Contains 1 ELMO domain.,similarity:Contains 1 PH domain.,subcellular location:Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.,subunit:Interacts with BAI1 (By similarity). Interacts directly with the SH3-domain of DOCK1 via its SH3-binding site. Part of a complex with DOCK1 and RAC1. Part of a complex with DOCK1 and CRK isoform CRK-II. Interacts with PLEKHG6.,tissue specificity:Widely expressed, with a higher expression in the spleen and placenta.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
組織表達： Widely expressed, with a higher expression in the spleen and placenta.
科研貨號： PLA018764

Elmo1 Polyclonal Antibody

Catalog No PLA018764

Product information

基因名稱： ELMO1
蛋白名稱： Engulfment and cell motility protein 1
Human_gene_id： 9844
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9844
Human_swiss_prot_no： Q92556
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q92556/entry
Mouse_gene_id： 140580
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140580
Mouse_swiss_prot_no： Q8BPU7
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8BPU7
特異性： Elmo1 Polyclonal Antibody detects endogenous levels of Elmo1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： ELMO1; KIAA0281; Engulfment and cell motility protein 1; Protein ced-12 homolog
實測條帶： 83kD
信號通路： Chemokine;
功能： function:Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.,PTM:Phosphorylated by HCK.,similarity:Contains 1 ELMO domain.,similarity:Contains 1 PH domain.,subcellular location:Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.,subunit:Interacts with BAI1 (By similarity). Interacts directly with the SH3-domain of DOCK1 via its SH3-binding site. Part of a complex with DOCK1 and RAC1. Part of a complex with DOCK1 and CRK isoform CRK-II. Interacts with PLEKHG6.,tissue specificity:Widely expressed, with a higher expression in the spleen and placenta.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細胞定位： Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
組織表達： Widely expressed, with a higher expression in the spleen and placenta.
科研貨號： PLA018764

Hunan UPT Biotechnology Co.,Ltd

Website：www.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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