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TRPV4 Polyclonal Antibody

商品貨號(hào)： PLA018774

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： TRPV4
蛋白名稱： Transient receptor potential cation channel subfamily V member 4
Human_gene_id： 59341
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59341
Human_swiss_prot_no： Q9HBA0
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9HBA0/entry
Mouse_gene_id： 63873
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=63873
Mouse_swiss_prot_no： Q9EPK8
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9EPK8
Rat_gene_id： 66026
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66026
Rat_swiss_prot_no： Q9ERZ8
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9ERZ8
特異性： TRPV4 Polyclonal Antibody detects endogenous levels of TRPV4 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TRPV4; VRL2; VROAC; Transient receptor potential cation channel subfamily V member 4; TrpV4; Osm-9-like TRP channel 4; OTRPC4; Transient receptor potential protein 12; TRP12;Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; VRL-2; Vanilloid receptor-related osmotically-activated channel; VR-OAC
實(shí)測(cè)條帶： 98kD
功能： disease:Defects in TRPV4 are the cause of brachyolmia type 3 [MIM:113500]; also called brachyrachia. The brachyolmias constitute a clinically and genetically heterogeneous group of skeletal dysplasias characterized by a short trunk, scoliosis and mild short stature. Type 3 brachyolmia is an autosomal dominant form with severe kyphoscoliosis and flattened, irregular cervical vertebrae.,function:Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.,similarity:Belongs to the transient receptor family. TrpV subfamily.,similarity:Contains 3 ANK repeats.,subcellular location:Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum.,subunit:Homotetramer (Probable). Self-associates in a isoform-specific manner. Isoforms 1/A and 5/D but not isoform 2/B, 4/C and 6/E can oligomerize. Interacts with calmodulin. Interacts with Map7 and Src family Tyr protein kinases LYN, SRC, FYN, HCK, LCK and YES.,
相關(guān)產(chǎn)品： YT5833,YT5040,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane . Apical cell membrane ; Multi-pass membrane protein . Cell junction, adherens junction . Cell projection, cilium . Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum. .; [Isoform 1]: Cell membrane .; [Isoform 5]: Cell membrane .; [Isoform 2]: Endoplasmic reticulum .; [Isoform 4]: Endoplasmic reticulum .; [Isoform 6]: Endoplasmic reticulum .
組織表達(dá)： Found in the synoviocytes from patients with (RA) and without (CTR) rheumatoid arthritis (at protein level).
科研貨號(hào)： PLA018774

TRPV4 Polyclonal Antibody

Catalog No PLA018774

Product information

基因名稱： TRPV4
蛋白名稱： Transient receptor potential cation channel subfamily V member 4
Human_gene_id： 59341
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59341
Human_swiss_prot_no： Q9HBA0
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9HBA0/entry
Mouse_gene_id： 63873
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=63873
Mouse_swiss_prot_no： Q9EPK8
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9EPK8
Rat_gene_id： 66026
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66026
Rat_swiss_prot_no： Q9ERZ8
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9ERZ8
特異性： TRPV4 Polyclonal Antibody detects endogenous levels of TRPV4 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： TRPV4; VRL2; VROAC; Transient receptor potential cation channel subfamily V member 4; TrpV4; Osm-9-like TRP channel 4; OTRPC4; Transient receptor potential protein 12; TRP12;Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; VRL-2; Vanilloid receptor-related osmotically-activated channel; VR-OAC
實(shí)測(cè)條帶： 98kD
功能： disease:Defects in TRPV4 are the cause of brachyolmia type 3 [MIM:113500]; also called brachyrachia. The brachyolmias constitute a clinically and genetically heterogeneous group of skeletal dysplasias characterized by a short trunk, scoliosis and mild short stature. Type 3 brachyolmia is an autosomal dominant form with severe kyphoscoliosis and flattened, irregular cervical vertebrae.,function:Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.,similarity:Belongs to the transient receptor family. TrpV subfamily.,similarity:Contains 3 ANK repeats.,subcellular location:Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum.,subunit:Homotetramer (Probable). Self-associates in a isoform-specific manner. Isoforms 1/A and 5/D but not isoform 2/B, 4/C and 6/E can oligomerize. Interacts with calmodulin. Interacts with Map7 and Src family Tyr protein kinases LYN, SRC, FYN, HCK, LCK and YES.,
相關(guān)產(chǎn)品： YT5833,YT5040,RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Cell membrane . Apical cell membrane ; Multi-pass membrane protein . Cell junction, adherens junction . Cell projection, cilium . Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum. .; [Isoform 1]: Cell membrane .; [Isoform 5]: Cell membrane .; [Isoform 2]: Endoplasmic reticulum .; [Isoform 4]: Endoplasmic reticulum .; [Isoform 6]: Endoplasmic reticulum .
組織表達(dá)： Found in the synoviocytes from patients with (RA) and without (CTR) rheumatoid arthritis (at protein level).
科研貨號(hào)： PLA018774

Hunan UPT Biotechnology Co.,Ltd

Website：www.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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