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SPTLC1 Polyclonal Antibody

商品貨號： PLA018940

適應(yīng) 性： 人,小鼠,大鼠

￥600元

規(guī)格：

40μL 100μL 200μL

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MSDS

說明書

商品描述

基因名稱： SPTLC1
蛋白名稱： Serine palmitoyltransferase 1
Human_gene_id： 10558
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10558
Human_swiss_prot_no： O15269
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15269/entry
Mouse_gene_id： 268656
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=268656
Mouse_swiss_prot_no： O35704
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35704
特異性： SPTLC1 Polyclonal Antibody detects endogenous levels of SPTLC1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： SPTLC1; LCB1; Serine palmitoyltransferase 1; Long chain base biosynthesis protein 1; LCB 1; Serine-palmitoyl-CoA transferase 1; SPT 1; SPT1
實(shí)測條帶： 52kD
信號通路： Sphingolipid metabolism;
功能： catalytic activity:Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO(2).,cofactor:Pyridoxal phosphate.,disease:Defects in SPTLC1 are the cause of hereditary sensory and autonomic neuropathy type 1 (HSAN1) [MIM:162400]. The hereditary sensory and autonomic neuropathies are a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN1 is an autosomal dominant axonal neuropathy with onset in the second or third decades. Initial symptoms are loss of pain, touch, heat, and cold sensation over the feet, followed by distal muscle wasting and weakness. Loss of pain sensation leads to chronic skin ulcers and distal amputations.,pathway:Lipid metabolism; sphingolipid metabolism.,similarity:Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.,subunit:SPTLC1, SPTLC2 and SPTLC3 may encode subunits of the enzyme.,tissue specificity:Widely expressed. Not detected in small intestine.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Endoplasmic reticulum membrane ; Single-pass membrane protein .
組織表達(dá)： Widely expressed. Not detected in small intestine.
科研貨號： PLA018940

SPTLC1 Polyclonal Antibody

Catalog No PLA018940

Product information

基因名稱： SPTLC1
蛋白名稱： Serine palmitoyltransferase 1
Human_gene_id： 10558
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10558
Human_swiss_prot_no： O15269
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15269/entry
Mouse_gene_id： 268656
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=268656
Mouse_swiss_prot_no： O35704
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35704
特異性： SPTLC1 Polyclonal Antibody detects endogenous levels of SPTLC1 protein.
組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
來源： Polyclonal, Rabbit,IgG
稀釋： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度： 1 mg/ml
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
說明書： 1
Msds： MSDS_Antibody.pdf
其他名稱： SPTLC1; LCB1; Serine palmitoyltransferase 1; Long chain base biosynthesis protein 1; LCB 1; Serine-palmitoyl-CoA transferase 1; SPT 1; SPT1
實(shí)測條帶： 52kD
信號通路： Sphingolipid metabolism;
功能： catalytic activity:Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO(2).,cofactor:Pyridoxal phosphate.,disease:Defects in SPTLC1 are the cause of hereditary sensory and autonomic neuropathy type 1 (HSAN1) [MIM:162400]. The hereditary sensory and autonomic neuropathies are a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN1 is an autosomal dominant axonal neuropathy with onset in the second or third decades. Initial symptoms are loss of pain, touch, heat, and cold sensation over the feet, followed by distal muscle wasting and weakness. Loss of pain sensation leads to chronic skin ulcers and distal amputations.,pathway:Lipid metabolism; sphingolipid metabolism.,similarity:Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.,subunit:SPTLC1, SPTLC2 and SPTLC3 may encode subunits of the enzyme.,tissue specificity:Widely expressed. Not detected in small intestine.,
相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
細(xì)胞定位： Endoplasmic reticulum membrane ; Single-pass membrane protein .
組織表達(dá)： Widely expressed. Not detected in small intestine.
科研貨號： PLA018940

Hunan UPT Biotechnology Co.,Ltd

Website：www.tjdqdt.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.

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