其他名稱(chēng): KLRC1; NKG2A; NKG2-A/NKG2-B type II integral membrane protein; CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; CD159a; KLRC2; NKG2C; NKG2-C type II integral membrane protein;CD159 antigen-like family member C; NK cell receptor C; NKG2-C-activating NK receptor; CD159c; KLRC3; NKG2E; NKG2-E type II integral membrane protein; NK cell receptor E; NKG2-E-activating NK receptor
實(shí)測(cè)條帶: 25kD
信號(hào)通路: Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease;
功能: function:Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.,online information:NKG-2A,similarity:Contains 1 C-type lectin domain.,subunit:Can form disulfide-bonded heterodimer with CD94.,tissue specificity:Natural killer cells.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Cell membrane ; Single-pass type II membrane protein .
組織表達(dá): Predominantly expressed in NK cells (at protein level) (PubMed:9430220, PubMed:9485206, PubMed:20952657). Expressed in intraepithelial CD8-positive T cell subsets with higher frequency in gamma-delta T cells than alpha-beta T cells (at protein level) (PubMed:18064301). Expressed in memory gamma-delta T cells (at protein level) (PubMed:20952657). Restricted to a subset of memory/effector CD8-positive alpha-beta T cells (at protein level) (PubMed:12387742). Expressed in intratumoral NK and CD8-positive T cells (PubMed:30503213). Expressed in melanoma-specific cytotoxic T cell clones (at protein level) (PubMed:9485206). KLRD1-KLRC1 and KLRD1-KLRC2 are differentially expressed in NK and T cell populations, with only minor subsets expressing both receptor complexes (at protein level) (PubMed:20952657).
科研貨號(hào): PLA018989
CD159a/c Polyclonal Antibody
Catalog NoPLA018989
Product information
基因名稱(chēng): KLRC1/KLRC2/KLRC3
蛋白名稱(chēng): NKG2-A/NKG2-B type II integral membrane protein/NKG2-C type II integral membrane protein/NKG2-E type II integral membrane protein
其他名稱(chēng): KLRC1; NKG2A; NKG2-A/NKG2-B type II integral membrane protein; CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; CD159a; KLRC2; NKG2C; NKG2-C type II integral membrane protein;CD159 antigen-like family member C; NK cell receptor C; NKG2-C-activating NK receptor; CD159c; KLRC3; NKG2E; NKG2-E type II integral membrane protein; NK cell receptor E; NKG2-E-activating NK receptor
實(shí)測(cè)條帶: 25kD
信號(hào)通路: Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease;
功能: function:Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.,online information:NKG-2A,similarity:Contains 1 C-type lectin domain.,subunit:Can form disulfide-bonded heterodimer with CD94.,tissue specificity:Natural killer cells.,
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Cell membrane ; Single-pass type II membrane protein .
組織表達(dá): Predominantly expressed in NK cells (at protein level) (PubMed:9430220, PubMed:9485206, PubMed:20952657). Expressed in intraepithelial CD8-positive T cell subsets with higher frequency in gamma-delta T cells than alpha-beta T cells (at protein level) (PubMed:18064301). Expressed in memory gamma-delta T cells (at protein level) (PubMed:20952657). Restricted to a subset of memory/effector CD8-positive alpha-beta T cells (at protein level) (PubMed:12387742). Expressed in intratumoral NK and CD8-positive T cells (PubMed:30503213). Expressed in melanoma-specific cytotoxic T cell clones (at protein level) (PubMed:9485206). KLRD1-KLRC1 and KLRD1-KLRC2 are differentially expressed in NK and T cell populations, with only minor subsets expressing both receptor complexes (at protein level) (PubMed:20952657).