其他名稱: TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2;ABIN-2;Fetal liver LKB1-interacting protein)
功能: function:Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation.,subunit:Interacts with STK11, TNFAIP3, IKBKG, NFKB1, MAP3K8 and RIPK1.,tissue specificity:Ubiquitously expressed in all tissues examined.,
相關產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細胞定位: Cytoplasm . Nucleus .
組織表達: Ubiquitously expressed in all tissues examined.
科研貨號: PLA019547
Abin-2 Polyclonal Antibody
Catalog NoPLA019547
Product information
基因名稱: TNIP2 ABIN2 FLIP1
蛋白名稱: TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)
其他名稱: TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2;ABIN-2;Fetal liver LKB1-interacting protein)
功能: function:Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation.,subunit:Interacts with STK11, TNFAIP3, IKBKG, NFKB1, MAP3K8 and RIPK1.,tissue specificity:Ubiquitously expressed in all tissues examined.,
相關產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細胞定位: Cytoplasm . Nucleus .
組織表達: Ubiquitously expressed in all tissues examined.