儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號(hào): PT1125R
特異性: Endogenous
基因名稱: CLEC2B,AICL,CLECSF2,IFNRG1
蛋白名稱: C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
別名: AICL CLECSF2 IFNRG1
Organism-1: Human
基因ID-1: 9976
SwissProt-1: Q92478
Organism-2: Mouse
背景: Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
細(xì)胞定位: SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23929856, ECO:0000269|PubMed:29980609}; Single-pass type II membrane protein {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:23929856}. Note=Resting NK cells contain intracellular stores of CLEC2B associated with the Golgi complex. {ECO:0000269|PubMed:23929856}.
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆號(hào): PT1125R
特異性: Endogenous
基因名稱: CLEC2B,AICL,CLECSF2,IFNRG1
蛋白名稱: C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
別名: AICL CLECSF2 IFNRG1
Organism-1: Human
基因ID-1: 9976
SwissProt-1: Q92478
Organism-2: Mouse
背景: Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
細(xì)胞定位: SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:23929856, ECO:0000269|PubMed:29980609}; Single-pass type II membrane protein {ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:23929856}. Note=Resting NK cells contain intracellular stores of CLEC2B associated with the Golgi complex. {ECO:0000269|PubMed:23929856}.